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Narsoplimab, a Mannan-binding lectin-associated serine protease-2 inhibitor, for the treatment of adult hematopoietic stem-cell transplantation-associated thrombotic microangiopathy

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The mean estimated FVC% was 97.0 at baseline, 72.7 at month 12 and 48.4 at month 24 in treated subjects, with a mean slope of 2.0, as compared to 97.4, 65.8 and 33.8 in not treated subjects, with a mean slope of 2.6 (slope difference: 0.6