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The first proposed use of POTABA to treat PD was in 1959 by Zarafonetis and Horrax (7)

Use cautiously if taking medication for hormone disorders, particularly 5-alpha-reductase inhibitors, as Astaxanthin may inhibit 5-alpha-reductase, preventing the conversion of testosterone to dihydrotestosterone (DHT) leading to decreased libido, gynecomastia, decreased semen quantity during ejaculation, impotence, increased skin pigmentation, hair growth, weight gain, and low mood

While an occasional protein shake is fine, replacing all meals with liquid calories often leads to blood sugar instability (liquid calories absorb faster) and inadequate satiety (chewing and the act of eating contribute to feeling satisfied)

The inflammatory response induced by RELM upregulates IL-8 and IL-1 expression in bronchial epithelial cells in COPD

Major cytokines secreted by T cells include IL-1, IL-4, IL-6, TGF-, leukoregulin, and IGF-1, while orbital fibroblasts release IL-1, IL-6, IL-8, IL-10, IL-12, MCP-1, and TNF- (114)