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Water Retention and Edema: Excessive growth hormone levels can cause swelling and bloating, leading to discomfort and potential cardiovascular strain

TRPV1 can affect NO synthesis by regulating nNOS enzyme activity 101

Antifibrotic Properties: Milk thistle affects the development of liver fibrosis, minimizing excessive scar tissue formation Enhances Bile Production : Milk thistle may enhance bile and bile acid excretion due to its high fiber content, which contributes to lowering cholesterol and triglyceride levels, with over 80% of the active compound being eliminated through bile

The complexity lies in liposomal validationa highly technical and costly process that many manufacturers avoid [3]

Three major metabolic pathways are involved in ceramide biosynthesis: the de novo, the salvage pathway and the sphingomyelinase pathway