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So you can still have PCOS with irregular periods and high testosterone but no ovarian cysts.23 Amenorrhea Amenorrhea is when youve either not gotten your first period by age 15 (primary) or missed your period for three or more months (secondary).25 Though it can be caused by a female hormonal imbalance, we dont recommend taking a supplement specifically for amenorrhea since many of its potential causes are medical conditions that warrant a doctors guidance or intervention