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However, in the complex molecular processes that characterize tumorigenesis, iron also plays a central role in ferroptosis, a form of non-apoptotic regulated cell death characterized by the lethal accumulation of lipid peroxidation products and ROS derived from iron metabolism (362, 363)

The dual mechanism of tirzepatide produces greater average weight loss in clinical trials, approximately 22% body weight versus 15% for semaglutide

Acknowledgement: We acknowledge the facilities provided by NCCS, Pune and the School of Biotechnology, DAVV for our experimental work

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