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This study provides a rationale for combination therapy strategies in future clinical trial design

Andreassen KV, Feigh M, Hjuler ST, Gydesen S, Henriksen JE, Beck-Nielsen H, et al

Peptides with cationic motifs utilize electrostatic interactions to target and bind negatively charged phospholipids in cell membranes, thereby facilitating their entry into cells 55

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Also, these signals recruit additional receptors into the post-synaptic membrane, stimulating the production of a modified receptor type, thereby facilitating an influx of calcium