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High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism

Zamanian MY, Soltani A, Khodarahmi Z, Alameri AA, Alwan AMR, Ramrez-Coronel AA, Obaid RF, Abosaooda M, Heidari M, Golmohammadi M, Anoush M (2023) Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: an overview and update on new developments

The outcome of this competition depends from the Cu(II)-binding affinities and concentrations of HSA, CuHSA and His according to the following simplified reaction scheme: HSA and His are present in the blood serum at average 650 M and 75 M concentration respectively 22,42,43,44