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IL-1 can activate NLRP3 inflammatory vesicles, upregulate cholesterol synthesis genes ( HMGCR / LDLR ) through the nuclear translocation of SCAP-SREBP2, and enhance glycolytic enzyme expression via mTORC1, thereby resulting in a metabolic amplification effect (50)

J Cell Sci (2015) 128:7080

[71] observed enhanced spermatogenesis, as reflected by higher Johnsen scores, in PRP-treated animals

It works with glutathione to boost its effects