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pH levels should align with ingredient stability (e.g., vitamin C formulations at pH 3.5 or lower)

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And then just to point out too, that on the other hand, randomized controlled trials have less of this issue of alopecia or hair loss

518,519 For EC5026, a single-ascending dose study (NCT04228302) and a fed-fasted study (NCT04908995) demonstrated good tolerability, with no adverse reactions associated with EC5026 observed during treatment