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Your clinician should walk you through your personal tretinoin game plan over time and answer any questions that you have, including how to layer products and perform the sandwiching technique, as well as what potentially irritating active ingredients to avoid using at the same time as tretinoin (AHAs, BHAs, benzoyl peroxide)

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RAW264.7 cells were fixed with 4% paraformaldehyde, permeabilized with ice-cold methanol, and blocked with MinuteBlock Blocking Buffer (Affinibody, China)

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10.1186/s13023-024-03421-5 100 KarakasisP.TheofilisP.PatouliasD.VlachakisP