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Its typically administered via subcutaneous injections

Furthermore, because fasting values affect the increase in postmethionine-load homocysteine, the percent rise of homocysteine above fasting should be taken into account when assessing the cardiovascular risk

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486 The SPACE trial tested the effect of vitamin E (800 IU/day) on a combined cardiovascular endpoint in 196 HD patients with pre-existing CVD, and showed a significant benefit from vitamin E supplementation

That said, some people report mild stomach upset, especially at higher doses