Ozempic, an injectable GLP-1 approved to regulate blood sugar in people with Type 2 diabetes, headed up the surge in popularity
Testing MTHFR and other relevant genetic markers can identify these individuals, though routine genetic testing for b12 supplementation decisions remains controversial
Dose Tolerance and Missed Doses If patients do not tolerate the 25 mg once-daily pill, consider switching to the once-weekly Wegovy pen 1.7 mg
Concomitant diseases included heart failure (23%), hypertension (91%), previous ischemic stroke (12%), previous MI (40%), and peripheral artery disease (16%)
The FDA's 2025 guidance for biosimilars aims to cut development time and cost in half by replacing expensive human studies with advanced analytical testing in cases where the science supports it, which could accelerate future approvals