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The company submitted applications to the FDA for two different regulatory approvals: one to market the product as a new tobacco product (called a Pre-Market approval) in March 2017, and the other to market the product as less harmful than other tobacco products (called a Modified Risk Tobacco Product approval) in December 2016

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The Centers for Disease Control and Prevention (CDC) suggests: Women under 25 Sexually active women should have a yearly Chlamydia test