Add Health, as the survey is known, began tracking over 20,000 middle school and high school students in 1994-1995 and has followed these students well into adulthood through three subsequent waves (in 1996, 2001-2002 and 2008)
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First, before the application deadline, the FDA represented that long-term studies were likely unnecessary and that applicants had discretion to use products that consumers are most likely to consider[] interchangeable when submitting comparative health risk data. PMTA Guidance at 13
Another thing to consider is that rooms that have AC installed tend to be more airtight, since the owner of the property will want to minimize his electricity bill
Also know that estimating is fine