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They get strong abdominal pain, like a punch in the gut, and it lasts for hours." After the acute reaction passes, Chadi says there is a period of feeling "limp, tired and unwell." He says the "intense" experience is so common among the teens he's treated that they refer to this "well-known pattern" as being "nic-sick." He argues that the condition is inextricably linked to the creation of certain ultra-powerful e-cigarettes like Juul, which contain exorbitantly high levels of nicotine (the CDC says that one Juul pod is the equivalent of an entire pack of cigarettes)