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To get around a potential lawsuit, Hollywood prop houses started creating fake cigarette brands that could be used in movie and TV productions

doi: 10.1093/toxsci/kfw166 [DOI] [PubMed] [Google Scholar] 25

By the 1980s, the number of machine-rolled kreteks exceeded the hand-rolled ones and today there are hundreds of companies employing millions of individuals

Cardiovascular effects Combustible cigarette smoking is one of the strongest preventable risk factors for cardiovascular disease.[28] Though the association between e-cigarette use and cardiovascular outcomes is largely unclear at this point, new data suggest that e-cigarettes are associated with cardiovascular morbidity [Table 2], though it is likely less than that of combustible cigarette smoking.[29] This section highlights the potential associations between e-cigarette use and cardiovascular disease, hypertension, endothelial health, and myocardial function

A third draft was delivered, but it did not - and could not, given the inherent weakness of the underlying survey - address the fundamental problems raised by the reviewer: that there was misclassification bias in the data, that there was likely to be reverse causation at work, and that the smokers who switched to vapes had quit smoking, on average, more recently than the other ex-smokers