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The systems toxicology approach integrates multi-level biological data to comprehensively understand systemic molecular and functional changes from an omics-based method using computational modeling to extrapolate classical toxicology findings to risk assessment 15,16

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oxygen level rises to normal 24 hours after quitting, chance of a heart attack decreases 48 hours after quitting, nerve endings start re-growing

Sci Rep 15 , 17945 (2025)