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EVIDENCE SUMMARY Bupropion is the only Food and Drug Administration (FDA)-approved antidepressant recommended as a first-line pharmacologic agent to assist with smoking cessation, based in part on a meta-analysis of 44 placebo-controlled RCTs (13,728 patients), which found that bupropion had a relative risk (RR) of 1.62 for smoking cessation compared with placebo (95% confidence interval [CI], 1.49-1.76)

Those experiencing withdrawal symptoms might also discuss drugs, such as nicotine replacement therapy, with medical specialists

Note: Dating of this cigarette case is approximate and based on the tube map on the inside of the cover - no York Road' Station, between Caledonian Road and Kings Cross Stations, it was closed in 1932 - and the map has 'Mark Lane' station next to Monument which was renamed Tower Hill in 1946

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The latter group comprised individuals who did not identify as Mori, Pacific or Asian, the large majority of whom were New Zealand European