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What to look for in your loved ones appearance: Dilated pupils Frequent runny nose Frequent nosebleeds Lost sense of smell Track marks Burned lips or fingers Weight loss Jaw clenching Profuse sweating Tremors and muscle twitches Headaches Increased heart rate Increased body temperature What to look for in your loved ones behavior: Odd sleeping patterns (A person addicted to cocaine can go a few days with no sleep.) Seeming dispersed/not being able to concentrate Restless or fidgety Anxiety Fatigue Lack of motivation Paranoia Extreme happiness and energy Overconfidence Aggressiveness Irritability Distrustful of others intentions Feelings of rage and/or hatred Antagonistic behaviors toward others Defensiveness Fearful Poor judgment Delusions Mood swings Paranoia Depression Since cocaine is a pretty expensive habit, you might also take note if someone you love starts experiencing money troubles, steals or begins asking you for money

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Endothelial cell migration is an important mechanism of vascular repair than can be disrupted in smokers due to endothelial dysfunction [25, 26]

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