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The Huangdi Neijing (Yellow Emperor's Inner Canon), one of the oldest and most influential works in Traditional Chinese Medicine, mentions moxibustion as a vital therapy for various ailments

2011, titled Tobacco addiction and psychological co-morbidities. Physically, nicotine affects the brains reward system, releasing neurotransmitters like dopamine, which leads to cravings and withdrawal symptoms when tobacco use is reduced or stopped