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We dont know how the body reacts to pure nicotine without these other chemicals it could have its own set of negative health consequences

The third group included patients who essentially never smoked either product (Pradre et al., 2026)

People not only used their own tobacco as currency, but they used that of others as well

For example, some changed their businesses focus or location, while others cited legislative changes (such as display bans and changes to vending machine requirements) as influencing the decision to stop selling

We found that prior to JUUL entry in Canadian city-level markets, no significant pre-trend was observed for cigarette sales after controlling for all relevant factors described in the main specification