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As the study authors explain: Our theory suggests that the psychoactive effects of CB1 receptor stimulation with THC may be a necessary accompaniment to cannabis-induced weight loss, because down-regulation of CB1 receptors is required for reduced BMI, and it is not yet clear whether microdosing will cause down-regulation

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The researchers examined the immediate effects of HTPs on the respiratory and cardiovascular systems, comparing these with traditional cigarette smoking and e-cigarette usage

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