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Abstract: Carcinogens from tobacco reach the colorectal mucosa through either the alimentary tract or the circulatory system and could possibly damage or alter expression of important cancer-related genes
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Packaged products can generally be used for up to two years, while loose tobacco usually has a shelf life of three months
Exercise forces the muscles to work harder, which increases the bodys breathing rate, resulting in a greater supply of oxygen to the muscles
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![The Growth of the Tobacco Trade [ ]](https://www.ushistory.org/us/images/gilray.jpg)
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