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Among private funders, there is a perception that the public sector is adequately dealing with the issue and that the need and opportunity for impact is greater outside the U.S

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Its actually true, I said with a shrug

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What is already known on this topic Smoking increases the risk of developing coronary heart disease and stroke Many smokers believe that cutting down the number of cigarettes they smoke substantially reduces their risk of developing tobacco related disorders Occasional individual studies and a meta-analysis of five studies in 1997 reported that light cigarette smoking (less than five per day) is associated with a higher than expected risk of coronary heart disease What this study adds Men who smoke about one cigarette per day have a 48% higher risk of heart disease than never smokers and a 25% higher risk of stroke (or 74% and 30%, respectively, when allowing for confounding factors) The estimates are higher in women: 57% for heart disease and 31% for stroke (or 119% and 46% when allowing for multiple confounders), again compared with never smokers