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Therefore, to further reduce residual confounding, we additionally adjusted for these variables based on the main model, including diabetes, asthma, autoimmune diseases, menstrual disorders (including excessive menstruation, irregular menses and dysmenorrhea), PCOS, dyslipidemia before the index date and number of unique medications used 1 year before the index date

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This mutants accumulation of higher energy and carbohydrates suggests enhanced metabolic activity and stress tolerance (Feng et al., 2023)

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