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Cutaneous side effects may result in poor patient adherence to treatment

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Smoking during this week can still dislodge the clot or irritate the healing tissues, potentially causing pain and delaying healing

In the case of women, as already mentioned, the relationship is not so obvious, but smoking has been shown to reduce fertilisation rates and increase the risk of ectopic pregnancy (implantation of the embryo outside the uterus), which poses a risk to the mothers health and prevents the pregnancy from going ahead