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Occasionally, substitutions of flavours/designs is necessary due to temporary or regional unavailability issues

The data, which comes from the 2011, 2012, and 2013 National Youth Tobacco surveys of middle and high school students, show that youth who had never smoked conventional cigarettes but who used e-cigarettes were almost twice as likely to have intentions* to smoke conventional cigarettes as those who had never used e-cigarettes

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Electronic cigarette solvents, Juul E-liquids, and biomarkers of exposure: in vivo evidence for Acrolein and Glycidol in E-cig-derived aerosols