Combustion alters the protein structure, but residual allergenicity may trigger reactions in allergic individuals
Over the last 50 years, other types of lung cancer have decreased as smoking rates have fallen but, strangely, cases of lung adenocarcinoma have increased
Indeed, within-state variation in cigarette smoking sometimes rivals variation seen in the country as a whole
However, other risk factors include exposure to radon, secondhand smoke, asbestos (particularly among smokers), certain metals (chromium, cadmium, arsenic), some organic chemicals, radiation, air pollution, and diesel exhaust
In the days before legalization, a blunts tobacco leaf wrap provided a discreet visual alternative to joints, while also disguising the distinctive odor of burning weed