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Clinical diagnoses of sporadic PD using recognised diagnostic criteria, including UK Brain Bank and Gelb diagnostic criteria and the Hoehn & Yahr and Unified Parkinson Disease Rating scales 3

In addition, memory impairment caused by hypothyroidism was revealed to be improved by nicotine via the modulation of calcineurin, which regulates the function of calmodulin-dependent protein kinase II (CaMKII) to improve synaptic plasticity (76)

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Smoke-free laws and restrictive smoking policies have quite literally pushed tobacco users into the back alley, out of sight for many of us