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June 25, 2008 1:03 PM Whirlygirl said

Chang SS, Jiang WW, Smith I, Glazer C, Sun W-Y, Mithani S, et al: Chronic cigarette smoke extract treatment selects for apoptotic dysfunction and mitochondrial mutations in minimally transformed oral keratinocytes

With regard to tobacco, not only the taste but also the retention of the accustomed burning behaviour is very important

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The main reason vaping gets you hooked is nicotine - the same ingredient that makes smokers crave cigarettes