Due to concerns for worsening suicidal thoughts and agitation, varenicline (Chantix) came under scrutiny in 2009
They are useful screening tools, with two specifics worth understanding
PLoS ONE 7:e43898 Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A (2019) Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma
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Your Brain Cigarettes release feel-good chemicals in your brain, having an effect on you that is similar to addictive drugs like heroin