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Our study provides compelling biological evidence that a specific genetic variant contributes to risk for schizophrenia, defines the mechanism responsible for the effect, and validates that nicotine improves that deficit. Jerry Stitzel The treatment applications of their findings may be even broader, given that people living with attention deficit hyperactivity disorder, PTSD, or bipolar disorder have all been This defines a completely novel strategy for medication development, says lead author Maskos

"We always measure and look at the intended effects, like encouraging people to quit smoking, but sometimes we don't remember to look at what else these messages are doing that we're not thinking about, like causing reactance," she said