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Papers with a range of air permeabilities were used for the porous area of the split-tipping (Additional file1: Table S1)

Although relying on CAC testing can lead to a missed opportunity for earlier intervention, it is important to acknowledge that it is unknown if the extra cost and radiation exposure of CCTA would offset the potential benefit of earlier intervention

Heydens, one of the recipients, noted in a separate message that we would be keeping the cost down by us doing the writing and [the outside scientists] would just edit and sign their names, so to speak. Their imprimatur would make the articles more credible to regulators and the public, he added

We doubled the sample size to 1,328 and added a 65% increase to decrease bias

He was one of the first managers I met who gave a pump-up speech