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52 Skosh : TAD Skosh is a slang term meaning a little bit, and was originally military slang that came out of the Korean War

In the case of marijuana, scientists have described acute problems with memory, coordination, and judgment, and chronic issues such as respiratory problems, cardiovascular disease, and cognitive impairment

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Larger amounts can overwhelm the entire nervous system

[61] Chronic nicotinic acetylcholine receptor activation from repeated nicotine exposure can induce strong effects on the brain, including changes in the brain's physiology, that result from the stimulation of regions of the brain associated with reward, pleasure, and anxiety