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Among these exposures, cigarette smoke is the most detrimental and, as the primary driver of COPD 5 and a common trigger of asthma exacerbations 6 , constitutes the leading cause of preventable death in the US 7

The strategy has seen success since its beginnings as a treatment option for epilepsy in the 1920s

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and reduces nuclear increase: p AIF = 0.047, p EndoG = 0.028)