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In previous studies, the authors had excluded smokers from ETS exposure impact estimations in order to obtain conservative estimates, but this approach does not take into account the possible synergistic effect of smoking plus ETS exposure in the causes of death studied

[24] The demand and profitability of tobacco led to the shift in the colonies to a slave-based labor force, fueling the Atlantic slave trade

After the Spanish successfully introduced tobacco to Europe and the British aristocracy adopted pipe smoking as a popular pastime, its increasing cultivation formed the economic basis of the first successful English colonies in north America.

Sweet with a touch of a salty flavor for that perfect blend

and the general respect of the law