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Nicotine abuse is not included in DSM-IV, but a related term harmful use is mentioned in ICD -10, which means that continued use causes physical problems

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Psychopharmacology 186:255263 Forget B, Guranda M, Gamaleddin I, Goldberg SR, Le Foll B (2016) Attenuation of cue-induced reinstatement of nicotine seeking by URB597 through cannabinoid CB1 receptor in rats

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