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When the mice were fed a diet deficient in choline, that is, lacking precursors required for DMG production, they failed to gain weight after smoking cessation. The second bioactive metabolite, acetylglycine, or ACG, followed a mirror-image pattern to that of DMG: Its levels were reduced during active exposure to smoke and after the exposure stopped, they increased following antibiotic treatment

Curr Pharm Des 24(14):14491484 Gimbrone MA Jr, Garca-Cardea G (2016) Endothelial cell dysfunction and the pathobiology of atherosclerosis

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Maternal cigarette smoking during pregnancy and the trajectory of externalizing and internalizing symptoms across childhood: similarities and differences across parent, teacher, and self reports