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One of the possible causes is that nicotine in tobacco smoke leads to oxidative stress and hence insufficient oxygen is supplied to the skin, which results in tissue ischemia and blood vessel occlusion

1 2 "Electronic Cigarettes: Their Constituents and Potential Links to Asthma"

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How smoking increases your risk of type 2 diabetes There are three main types of diabetestype 1, type 2 and gestational diabetes

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