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Davidson and de Silva also claimed that the analysis conducted by the Australian government of the effectiveness of plain packaging "fails on a number of criteria, including independence, transparency, replication and rigour." Morris said other factors could account for the decrease in Australian smoking rates, including the rise in the price of cigarettes, which were hit with a tax around the same time plain packaging was introduced

Validation with respect to disease risk implies that variation in biomarker levels in product users are predictive of variations in disease outcomes

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