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In order to keep things interesting on screen, the actors needed to keep moving without being distracted

He says he expected to see mass marketing and branding of marijuana over time

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A more sophisticated model has been replaced by the standard graded response paradigm (147), where ROS and reactive nitrogen species (RNS) interact dynamically, both as site-specific mediators and as core inflammatory regulators (148150)

The series is beloved even today, but the concept was a hard sell before production began