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doi: 45

6 found that men and women who were married to a current smoker were less likely to quit smoking, and women who were married to a former smoker were more likely to quit 6

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Yet, considering the importance of mitochondrial dysfunction in COPD and the increasing evidence highlighting mtDNA gene expression and methylation as potential biomarkers in a variety of diseases related to mitochondrial dysfunction and ageing, future studies may explore the impact of age and smoking status of COPD patients to provide a deeper understanding on mtDNA methylation and gene expression