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Discussion We demonstrated in Figure 2 that the cotinine concentration in serum samples could be detected by using a sensitive capillary electrophoresis method, in which micellar electrokinetic chromatography (MEKC) was combined with on-line concentration techniques, cation-selective exhaustive injection (CSEI) and sweeping

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[1] Cotinine's longer half-life allows it to be detected for a longer time in saliva, blood, and urine, making it the preferred marker for assessing tobacco use or nicotine exposure