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A recent review by Hiilamo and colleagues observed that, as the salience of health warnings on packs increased, the tobacco industry response moved from a position of relatively innocuous to increasingly litigious [19]

E-cigarette use and smoking uptake Given the extreme harms of smoking, understanding the likely relation of e-cigarette use to smoking uptake in youth and relapse in ex-smokers is important to quantifying their overall effects on health the topics of these systematic reviews of the world-wide evidence

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The UK Biobank study showed a low response rate of 5.5% and possible volunteers bias may be involved