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49-53 Nicotine also dysregulates ions and glucose transporters (GLUT1 and GLUT3) in cerebral microvessels and increases BBB permeability, in part by reducing the expression ofand adversely alteringthe cellular distribution of several tight junction proteins

These cigars measure 52 inches in diameter and 7.5 inches in length

Note: - There might be a bit color distortions due to different computer resolutions

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