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The International agency for research on cancer in 2004 classified areca nut as a human carcinogen group which mixed with tobacco increased the product risk nearly 15 times [13]

Popcorn Lung and Cryptogenic Organizing Pneumonia Although rare, some people who vape have developed bronchiolitis obliterans, also called popcorn lung, and cryptogenic organizing pneumonia (COP), formerly known as bronchiolitis obliterans organizing pneumonia (BOOP)

Snus and nasal snuff also allow for nicotine administration outside of tobacco smoking