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DNA damage from tobacco use has been associated with a higher risk of birth defects

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While smokeless tobacco has demonstrably less carcinogens and toxins than cigarette smoke, said Hecht, smokeless tobacco still has remarkably high levels of carcinogenic tobacco-specific nitrosamines levels that are 100 to 1,000 times higher than in any other consumer product that is designed for oral consumption. In a separate study, the team evaluated carcinogen biomarker levels in individuals using these products