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Companies including New York-based Philip Morris International, which sells Marlboro outside the U.S., and British American Tobacco Plc, whose brands include Dunhill and Lucky Strike, are in a global battle against moves to curtail branding and make cigarettes unappealing

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Experimental studies in Wistar rats treated with PZA or PA showed hepatotoxicity, as demonstrated by elevated serum alanine aminotransferase, aspartate transaminase, and galactose single-point levels (Tostmann et al., 2008

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Theyd also know that traditional approaches to quitting (hello, cold turkey and nicotine-replacement therapy) have proved depressingly ineffective, especially among heavily addicted, low-income, longtime smokers: the folks who need our help the most