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(C) If an ACO is not eligible to receive a prior savings adjustment under 425.658(b)(3)(i), and the regional adjustment, expressed as a single value as described in 425.656(d), is negative or zero, the ACO will not receive an adjustment to its benchmark

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One country, for example, may prioritise keeping novel products out of the marketplace to forestall the expansion of overall tobacco use, while another may lower barriers to entry as part of an overall strategy to reduce smoking specifically

Smoking can negatively impact male fertility by reducing sperm quality, quantity, and motility

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