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To mitigate the inevitable issue of multicollinearity and potential effect modification among age at initiation, baseline age, and total pack-years, we based our analyses on a large population-wide cohort that allowed stratified analyses according to total pack-years of smoking exposure

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High-VG e-liquid (60% VG or above) is too thick to be absorbed by the coils used in normal vape pens, and will give you an unpleasant taste

They also may or may not contain caffeine, THC, CBD, or other psychoactive substances dissolved into a liquid base